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Communicable Disease Control Program

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You are here: Health Home > Communicable Disease Control > A-Z Diseases > Syphilis

Symptoms of Syphilis

Syphilis Fact Sheet (PDF 73 KB)

Primary Stage

In primary stage syphilis, a single sore (called a chancre) or multiple sores appear in the genital area. The chancre can appear within ten days to three months after exposure, and it is found on the part of the body that was exposed to the infected partner’s sore, such as the penis, vulva, or vagina. Because the chancre is small and painless, the infected person may not notice it. The chancre disappears within a few weeks, whether or not a person is treated. If not treated during the primary stage, the infection will go on to the secondary stage.

Secondary Stage

This stage typically starts as a skin rash, with brown sores about the size of a penny. The rash may cover the whole body or appear in just a few areas, but it is almost always on the palms of the hands and the bottoms of the feet. Active bacteria are present in these sores, and any physical contact with the broken skin of the infected person may spread the infection at this stage. The rash usually heals within several weeks or months.

Other symptoms may also occur, such as mild fever, sore throat, patchy hair loss, and swollen lymph glands. These symptoms may be very mild, and like the primary stage, will disappear with or without treatment. The signs of secondary syphilis may come and go over the next one to two years.

Tertiary (late) Stage

If untreated, syphilis may progress to a stage in which the disease is no longer contagious and no symptoms are present.. Infection remains in the body, however, and the bacteria can damage the heart, eyes, brain, nervous system, bones, joints, or almost any other part of the body. This stage can last for years or decades and can result in mental illness, blindness, heart disease, and death.


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Syphilis : General Information | Symptoms | Prevention | Diagnosis | Treatment | Resources


Please Note: All information is general in nature and should not substitute seeking proper medical attention.

Citation: This information has been compiled from resources provided by the Centers for Disease Control (CDC). For more information on the CDC, visit their website at: http://www.cdc.gov/.


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