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Immunization Program

3450 Broadway
Boulder, CO 80304
(303)413-7500

Boulder County Public Health

3450 Broadway
Boulder, CO 80304
(303) 441-1100


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Tdap Vaccine Safety

Tdap Vaccine Fact Sheet (PDF 39 KB) Español (PDF 237 KB)

A person who gets tetanus, diphtheria, or pertussis disease is at much higher risk of severe complications than a person who gets Tdap vaccine. During clinical trials (testing before the vaccine was licensed) involving about 4,000 adolescents, the following problems were reported:

Mild Problems

  • Pain (about 7 in 10)
  • Redness or swelling (about 1 in 5)
  • Mild fever (at least 99.5°F) (up to about 1 in 10)
  • Headache (about 4 in 10)
  • Tiredness (less than 1 in 3)
  • Nausea, vomiting, diarrhea (about 1 in 5)
  • Other mild problems reported include chills, body aches, sore joints, rash, and swollen lymph nodes.

Moderate Problems

  • Severe pain at the injection site (about 1 in 20)
  • Severe redness or swelling (up to about 1 in 16)
  • Fever over 102°F (about 1 in 100)

Severe Problems

  • None found

Tdap: Vaccine | Disease | Safety | Questions & Answers


Please Note: All information is general in nature and should
not substitute seeking proper medical attention.

Citation: This information has been compiled from resources provided by the Centers for Disease Control (CDC). For more information on the CDC, visit their website at: www.cdc.gov/.


Immunization Program
Boulder County Public Health

3450 Broadway, Boulder, CO 80304, (303) 413-7500

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